Upstate Medical University

MDIC Graduate Milestones

Medical Device Innovation Challenge (MDIC) Graduate Milestones (2017 – Present)

Total Federal Grants

 $ 9,883,762

Total Non-federal Grants/Investments


Total Employees Hired




EndoGlow* – Tissue Reveal Technology™  (

  • Non Government Funds Awarded:  $330,000 (pre-seed)
  • $100,000 FuzeHub Manufacturing Grants
  • Prototype and preclinical testing completed with University of Rochester
  • Named by Med Tech Outlook as a Top 10 Minimally Invasive Device Solution Company
  • Accepted into Cornell Center for Materials Research (CCMR)
  • Accepted into Venture Creation Innovation Challenge
  • Hires: CEO, COO, VP of Business Development and National Sales Manager
  • Won MedTech 2021 Innovative Surgical Device Company Award
  • FDA device registration complete
  • Cadaver labs teaching NIR in partnership with STORZ (Albany Medical Center, University of Rochester)
  • PreClinic research presented at the Society of Gynecologic Surgeons 3/2022
  • Working with KOLs on clinical research studies involving complex pelvic anatomy 
  • Paula J. Doyle, MD, CEO and Founder of EndoGlow selected as an American Medical Women’s Association (AMWA) Healthcare Innovation Challenge Start-up Pitch Finalist

Costello Prosthetic Warmers (

  • Project accepted by Queen’s University Human Mobility Center student capstone project
  • Participated in MedTech Annual Conference Pitch Event (October, 2017)
  • Prototype tested in Denali mountain climb
  • Licensing proposal with large manufacturer in process


Avant Medical Systems – Smart backboard

  • Marketed their technology with industry partners Health O Meter and Marsden

AcceliPHI (subsidiary of ANDRO) – Spinal device

  • Gained patent for individuals suffering from chronic back injuries


ZEPHYRx®* – Spirometry Technology/Remote Patient Monitoring (

  • Received $225,000 NHLBI SBIR grant for development and testing of breath-controlled video game for respiratory therapy
  • Resident company of Johnson & Johnson Innovation, JLABS, life science incubator program
  • Grew from 2 employees to 15 full-time employees
  • Pivoted to bring telemedicine to lung patients during pandemic with unique software program for at-home pulmonary function testing; exploded nationally in telemedicine market
  • Cystic Fibrosis Foundation purchases devices for every patient with cystic fibrosis in the US
  • Over $2.5M in product sales/contracts


Halomine – Rechargeable Antimicrobial Technology (

  • Federal Grants Awarded:
      $   600,000 (USDA Phase II)             $1,000,000 (NSF Phase II)
      $   175,000 (USDA Phase I)                               $2,000,000 (NYS ESD BioDefense Fund)
      $1,743,507 (NIH Phase II SBIR)                         $   100,000 (USDA Phase I SBIR)
      $     60,000 (Tech Search 3.0, US Army)           $       5,000 (Tech Search 5.0, US Army)
      $   225,000 (NSF Phase I SBIR)                         $   256,000 (NSF Phase I SBIR)
      $   250,255 (NIH Phase I SBIR)                          $   100,000 (DoD Phase I SBIR)
      $1,000,000 (USDA Phase III)                              $   325,000 (NIH Phase I)
  • Non-government funding: $1,207,500; Pre-seed; $2,885,000 SAFE
  • Cornell University spin out company
  • Funding support through Cornell Center for Materials Research (CCMR)
  • Joined Plug and Play Tech Center and New Materials 2020 Accelerator Program
  • Accepted into IndieBio inaugural NY program
  • Awarded $1M NSF SBIR Phase II grant to advance product development
  • Hired 15 employees including Dr. Xuehong Ren, one of the world’s leading authorities on synthesized monomers polymers and N-halamine chemistries as Chief Scientific Officer
  • 2023: Awarded both a $1M USDA Phase III and $325K NIH Phase I funds

MedUx – User-centered Designed Products (

  • Accepted into MassChallenge Boston Accelerator
  • Placed 2nd in ACC InVenture Prize Competition


Aurie* – Reusable Intermittent Catheter System (

  • Federal Grants Awarded:
    $1,776,000 (NSF)                                               $   500,000 (DoD)                                        
    $   100,000 (NIDILRR)                                        $   575,000 (NIDILRR)
  • $7,250,000 Investment
  • Employees Hired:  3.5
  • Accepted into Harvard LaunchLab X GEO and VentureWell ASPIRE
  • Won FuzeHub Commercialization Competition Awards
  • Awarded FuzeHub Manufacturing Grants totaling $150,000
  • Awarded Small Business Innovation Research (SBIR) grants from National Science Foundation and National Institute of Disability, Independent Living and Rehabilitation Research
  • Raised $750K in funding through pre-seed round led by Lakehouse Ventures
  • Received FDA Safer Technology Designation from FDA
  • Awarded $575,000 Phase II NIDILRR SBIR Award to further development of automated, reusable no-touch catheter system
  • CEO Souvik Paul serves as an MDIC Mentor


Assistance in Motion - Powered Ride-on Device for Children with Motor Impairments

  • Received SBIR Phase I Award of $256,000 to develop WeeBot, an infant-controlled powered ride-on device for children with motor impairments



Vita Innovations – Smart mask tracking signs of clinical deterioration (

  • Won A.I. Health Hackathon, Weill Cornell Medicine
  • Won 46th Annual Business Today International Conference Impact Challenge
  • Accepted into Blackstone & Techstars LaunchPad Fellowship
  • Collaborating with Hudson Valley Advanced Manufacturing Center and MTEC
  • Awarded Cornell University Student Business of the Year (2021)
  • Co-winner of the Verizon and Clinton Global Initiative 2021 Social Innovation Challenge
  • Accepted into MassChallenge Early-Stage National Startup Accelerator
  • Accepted and awarded grant funding from Venturewell Phase I and II E-Teams Accelerator
  • Accepted and awarded grant funding from American Heart Association National Business Accelerator
  • Received investment and product support from Nextfab Ventures
  • Completed Phase I User-Experience Trials at an academic hospital
  • Accepted into Stanford Venture Studios


MindTrace - 3D Neurosurgery Brain Mapping Technology (

  • Accepted into AlphaLab, Healthcare and life sciences accelerator
  • Working with SUNY Upstate Medical University neurosurgeon and Co-director of Upstate’s brain tumor program, Dr. Harish Babu, for clinical studies
  • Completed first stage of FDA Payor Communication Task Force
  • Pre-sub planned with FDA to submit via Breakthrough Device Designation
  • Selected by CB Insight’s as one of 150 most promising digital health companies of 2022

Rubitection - Skin Health Assessment Technology (

  • Presented at Medica Health Tech Conference
  • Selected as a finalist, Women of Color Health & Wellness Pitch
  • Awarded 2022 Health Equity Flex Grant, West Coast Consortium for Technology & Innovation in Pediatrics
  • Won 1st place at the National Black MBA Association #scaleuppitch competition

JelikaLite* - Precision Autism Technology (

  • Awarded$256,000 (NSF Phase I) for EEG-guided intelligent transcranial photobiomodulation to reduce symptoms of autism
  • Received $800,000 Investment
  • Accepted into Multiple Hub, Endless Frontier, M7, NYC Healthcare Program
  • Won FuzeHub Commercialization Competition Award
  • Participated in Syracuse University Student Engineering Capstone Program
  • Completed pivotal clinical trial, presented results at Rutgers University Autism Conference
  • Presented at 68th Annual Meeting of American Academy of Child and Adolescent Psychiatry
  • Presented at Symphony Conference, Brain Foundation
  • Granted FDA Breakthrough Device Designation
  • Completed 2 FDA Pre Submission meetings
  • Completed NSF-funded open label study, replicating 2021 clinical trial results showing autistic subject significant improvements in communications and responsiveness
  • Started pivotal clinical study at Upstate Medical University towards FDA marketing submission



Oratel Diagnostics - Endometriosis Diagnostic (

  • Patent filed: PCT/EP2022/081362
  • Consortium for Technology & Innovation in Pediatrics (CTIP) award of $7500
  • Completed first prototype using 3-D printing to evaluate our collection of saliva samples and develop standards to monitor reader performance
  • Completed data analysis on pre-clinical study with Brigham and Women’s Hospital on 181 patients
  • Presented at 15th World Congress on Endometriosis, Edinburgh, Scotland re Pilot Study of Saliva-Based Assay to Diagnose Endometriosis, May 2023
  • Completed Endimetrix prototype digital reader
  • Sponsored study at Alfred University Material Science Department to test difference in glass surfaces
  • Accepted by NSF to apply for STTR grant for 2023
  • Received $10,000 CTIP Flexi Grant Award working with Dr. Monica Guisti at Ohio State University to investigate chemistry of mechanism of action for Endimetrix diagnostic
  • Received $6,000 CTIP funding to assist with regulatory and marketing needs.

Dancing Eyes* - Eye Movement Disorder Technology

  • SUNY Upstate Medical University faculty-founded startup company
  • Completed University of Rochester regional I-Corps program
  • Working with Rensselaer Polytechnic Institute (RPI), Student Engineering Capstone Program


EndObetes – Endoscopic reversible treatment devices for obesity and diabetes (

  • Angel investment, $350K
  • SBIR Phase I NIH $256K, work completed
  • Strategic partnership with MicroTech Endoscopy
  • Completed MedTech Innovator Accelerator Program
  • Coordinated FDA Pre Submission meeting
  • Preclinical testing planned with SUNY Binghamton

PreTip* – Point of care EEG device for rapid screening in ED/ICU

  • Upstate Medical University faculty founded company
  • Phase II SBIR planning in process
  • Upstate Medical University faculty-founded company

PapEasy – cervical self-screening technology (

  • Coordinating with regulatory consultant for FDA submission
  • NSF SBIR Phase I submission in process
  • Working with Buffalo area contract manufacturer
  • CNYBAC Virtual Client

SurgiVance – point of care rapid diagnosis through diagnostic imaging using advanced optics (

  • Accepted into RPI student capstone program
  • In process of hiring CEO
  • FDA Pre-Submission in process/seed meeting scheduled
  • Submitted Phase II NIH SBIR




3Dspine – 3d printed modeling pre-operative planning for adult spine procedures

  • IP submitted through University at Buffalo
  • FDA and reimbursement pathway initiated
  • Planned STTR submission in 2023


2023 – Current MDIC Teams Milestones to-date

Advanced Gene Transfer Company – AGTC (carbon nanotube technology to expedite cellular immunotherapy production)

  • Submitted Phase I STTR
  • Initial discussions with Launch NY
  • Team invited to submit full proposal to The Advanced Research Projects Agency for Health (ARPA-H), nationwide health innovation network

BiRed Imaging (breast cancer adjunctive screening technology)

  • Closed $125K SAFE with RIT Venture Fund
  • Working with regional NYS-based manufacturer
  • Submitted to NY Ventures

CoreHaptics (game-based physical and cognitive therapy device)

  • Participated in SUNY Startup Summer School Pitch
  • Customer discovery with clinical experts
  • SBIR submission in process with InteliSpark

Lighthanded Enterprises (laser otoscope)

  • Accepted into Venture Well Aspire Program
  • Will be conducing usability pilot in CNY-area pediatric clinic

PodoSight (Upstate-founded foot tissue disruption monitor)

  • Provisional patent filed
  • Early discussion with Upstate Joslin Diabetes Clinic and Wound Care Center
  • Attending I-Corps short course, submission to SUNY Binghamton I-Corps for microgrant

*CNYBAC Clients